The main objective of the present study was to analyze burnout syndrome, ways of coping with stress, mental health and, specifically, to detect mental health predictors. The sample consisted of 152 non-university teachers between 24 and 58 years of age. We performed a descriptive exploratory study using the Maslach Burnout Inventory (Maslach & Jackson, 1981), the Ways of Coping Questionnaire (Folkman & Lazarus, 1988), and the General Health Questionnaire (Goldberg y William, 1972). The results indicate that the sample of teachers presented a medium degree of burnout. The most frequent strategies of coping with stress are: seeking social support, planning, and positive reappraisal. 40.8% of the sample had mental health problems. It was also found that a high level of stress was significantly associated with the escape-avoidance coping strategy, and that those teachers who were the least satisfied professionally were the most “burnt-out”. The variables of job, assessment of stress level, degree of commitment, emotional exhaustion, ways of coping escape-avoidance, and positive reappraisal contribute significantly to predict the teachers’ mental health.