The relationship between anxiety and drug use is bidirectional: on the one hand, the continued use of a psychoactive substance can produce anxiety symptoms; on the other hand, some anxiety disorders may worsen if the person consumes drugs. There are many different ways of consuming psychoactive substances; therefore it is necessary to bear in mind the psychosocial variables that affect the person who decides to consume psychoactive substances, as well as the motivations that led him to this behavior. There are many reasons for drug use: being accepted by the group, seeking pleasure, escaping from loneliness, seeking new experiences, finding their own identity, therapeutic use, etc. In all cases, the relationship with the social environment is an important factor in explaining the relationship between anxiety and psychoactive substances addiction. It seems logical that having many social resources can protect us from anxiety and drug use. However, some recent social changes, especially those related to technology, can create uncertainty in some people. This uncertainty, associated with low social skills, can lead some people to drug use. From this approach and the results of the latest research, this article deals on the assessment and psychological treatments in anxiety disorders induced by psychoactive substances, looking for a proactive intervention, in terms of psychosocial and educational advancement in prevention of drug use.